1) Dr. Abhimanu Kumar, MSc-Anatomy, PhD-Anatomy, MBA-Hospital Administration, Assistant Professor, Department of Anatomy, Ram Krishna Medical College Hospital and Research Centre, Bhopal. https://orcid.org/0009-0009-8626-7729
2) Dr. Abhishek Sen, MS-Anatomy, Assistant Professor, Department of Anatomy, Ram Krishna Medical College Hospital and Research Centre, Bhopal.
Abstract:
Introduction: The study likely investigates how high hypertension in mothers from central India affects the morphology and histopathology of vascular patterns within the finger-like projections of placentas. These villi are crucial for exchange of nutrients and oxygen between mother and fetus. The research likely compares placentas from mothers with hypertension to those from healthy mothers (non-hypertensive) to identify changes in the villi's blood vessel patterns caused by high blood pressure. This could help understand how hypertension might disrupt vital exchanges within the placenta and potentially impact fetal health.
Materials and Methods: Obstetrics and Gynecology Department, Department of Anatomy, Ram Krishna Medical Hospital and Research Centre, Bhopal, Madhya Pradesh. Study Population: 46 Placentas from both hypertensive (e.g., gestational hypertension, preeclampsia) and non-hypertensive mothers.
Methods: The study likely involved collecting and analyzing placental tissue samples from two groups: mothers with hypertension and mothers with normal blood pressure during pregnancy. Researchers would have examined the placentas for: Macroscopic morphology, histopathology Measuring size, weight, and shape of the placenta, Examining tissue samples under a microscope to identify changes in blood vessel structure, presence of abnormal cells, or deposits within the chorionic villi (finger-like projections responsible for nutrient and oxygen exchange).
Objective: To investigate the morphological (shape and size) and histopathological (microscopic tissue structure) alterations in the chorionic vascular patterns of placentas delivered by mothers with hypertension compared to those from normotensive (healthy blood pressure) mothers in Central India.
Expected Results: The study likely expects to identify differences in the morphology and histopathology of the chorionic vascular patterns between the hypertensive and non-hypertensive groups. These differences might include: Reduced size or weight of placentas in the hypertensive group, Changes in blood vessel size or distribution within the villi, Evidence of cell damage
Keyword: Placenta, Chorionic, Vascular, Hypertensive, Histopathology.
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