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Steroid therapy for patients with septic shock: A multicenter observational study conducted in Punjabi population.

JSCCR

Dr. Jaskaran Singh,1  Dr. Abhimanu Kumar2,  Dr. B.K Aggarwal3

1)    Dr. Jaskaran Singh, MBBS (Batch 2016-2021) from Maharishi Markandeswar Institute of Medical Science and Research, Mullana, Ambala

2)    Dr. Abhimanu Kumar, Assistant Professor, Department of Anatomy, Ram Krishna Medical College Hospital and Research Centre

3)    Dr. B.K Aggarwal, Professor, Department of General Medicine & Principal of Maharishi Markandeswar Institute of Medical Science and Research, Mullana, Ambala, Haryana, India.

 

 

Abstract:

Background: Septic shock is a life-threatening condition and current guidelines weakly recommend steroid use for resistant cases. This study examines real-world practices and outcomes of steroid therapy in septic shock patients from Punjab, India.

Methods: A multicenter, observational study reviewed adult intensive care unit (ICU) patients admitted with septic shock between January-March 2018. Patients who received vasopressors within 72 hours of admission were included. The analysis focused on comparing outcomes between patients who did and did not receive steroids, with further evaluation of intermittent vs. continuous steroid administration.

Results: (details to be filled after reading the study)

  • A total of X patients with septic shock were included.

  • X% received steroid therapy (intermittent or continuous).

  • Steroid use patterns and patient characteristics will be described.

  • The association between steroid administration type (intermittent/continuous) and shock reversal on day 7, as well as ICU mortality, will be analyzed using adjusted logistic regression.

Conclusions: This study will provide insights into how steroids are used for septic shock in Punjab, India. It will assess whether intermittent or continuous steroid administration is linked to improved patient outcomes like shock reversal and ICU survival

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